Moreover, MYF5 and MYOD are commonly re-expressed in experimental animal models of RMS irrespective of the cell of origin (Hettmer et al., 2011, 2015; Ignatius et al., 2012; Langenau et al., 2007; Rubin et al., 2011; Storer et al., 2013) suggesting roles for these transcription factors in driving tumor growth and TPC function. The gene discussed is MYOD1; the disease is neoplasm.