Transcriptional profiling of bulk tumor cells by qRT-PCR confirmed that mylpfa:myf5 expressing ERMS cells had high myf5 transgene expression, were more differentiated, and yet also had elevated expression of TPC-associated markers including c-met and cadherin 15 (Figure 1G, Langenau et al., 2007; Ignatius et al., 2012). The gene discussed is CDH15; the disease is neoplasm.