CASP3 and autoimmune polyendocrinopathy: Figure 5c shows that six serum samples were inhibited by the presence of the DI peptide to different degrees. Figure 5d compares the reduction in cleaved caspase-3 caused by DI in cultured cardiomyocytes exposed to APS IgG samples from individual patients with the percentage by which binding to β2GPI of the same APS IgG samples is inhibited by DI at the same concentration (40 μg/ml). There was a positive correlation between these two separate measures of DI inhibition of these samples (r=0.6775, P=0.0459).