MAPT and AIDS dementia complex: Gisslén et al.56 have analyzed t-tau and p-tau levels in 86 HIV-1+subjects including 21 of them with AIDS dementia complex (ADC) in a cross-sectional study demonstrating that while some ADC and HIV-1+infected patients had high t-tau in their CSF, there was no increase in p-tau levels unlike those seen in Alzheimers' patients.