VEGFA and ischemic stroke: We then studied the expression of VEGF-A, a neuroprotective molecule in the CNS16 including after ischemic stroke.17 We observed a twofold increase of VEGF-A in the ipsilateral cortex of ischemic WT mice treated with rtPA compared with untreated ischemic WT mice or sham-operated WT counterparts (Figures 7a and b: +110.7% in ischemic WT mice treated with rtPA compared with untreated ischemic WT mice, P=0.0209).