TUBB and cancer: As an anticancer drug, paclitaxel binds specifically in reversible manner to N-terminal 31 amino acids to the beta-tubulin subunit in the microtubules, which later inhibits microtubule formation.[5] For this reason, paclitaxel could restrict the effect that cancer cells strengthen their proliferation and metastasis by hyperplasia of capillaries.[42] With a view to the specific treatment target of paclitaxel, it is reasonable that paclitaxel produces lower toxicity to human body.