The combination of the 3-miRNA panel and AFP for discriminating HCC (all stages) from healthy control was analyzed by a stepwise logistic regression model [logit (p) = −1.545 + 0.403 × (miR-92-3p) + 0.919 × (miR-107) − 0.944 × (miR-3126-5p)+0.079 × (AFP)] (Supplementary Table 2). The gene discussed is AFP; the disease is hepatocellular carcinoma.