Previous clinical studies stated that the serum pro-inflammatory cytokines were remarkably elevated in HTG patients26, 27, consistently, Liu et al. 12 who established HTG-AP model with ApoCIII-tg mice joint Cae, also declared that the monocyte migration and pancreatic injury, along with the expression of inflammatory cytokines, such as TNF-a, IL-6, MCP-1 of HTG group were significantly higher than those of the wild type mice. Here, IL6 is linked to alkaline phosphatase measurement.