Although our current (Figs 1 and 2) and previous data8, 22 show that the AhR is also a potent suppressor of smoke-induced pulmonary inflammation, these data do not support that miR-135b contributes significantly to the ability of the AhR to attenuate inflammation, given that there was no significant difference in miR-135b induction between Ahr−/− and Ahr+/− mice. This evidence concerns the gene AHR and inflammation.