Gender, histological type, disease type, or treatment with EGFR-TKIs were enrolled in a univariate analysis, and the results showed that the median OS of patients who were female, or had adenocarcinoma or recurrent disease, or received EGFR-TKI therapy had a significantly longer OS than patients who were male, or had squamous or metastatic disease, or were not treated with EGFR-TKIs (Table 3). The gene discussed is EGFR; the disease is metastatic neoplasm.