Of note, there are nine genes among these targets that when mutated are known causes for inherited peripheral neuropathies (IPN) and hereditary spastic paraplegia (HSP) (Inf2, Sox10, Wnk1, Med25, Fa2h, Bscl2, Slc12a6, Kif1a and Kif5a) [13, 21, 29, 31, 40–42, 52]. This evidence concerns the gene KIF1A and hereditary spastic paraplegia.