MED25 and hereditary spastic paraplegia: Of note, there are nine genes among these targets that when mutated are known causes for inherited peripheral neuropathies (IPN) and hereditary spastic paraplegia (HSP) (Inf2, Sox10, Wnk1, Med25, Fa2h, Bscl2, Slc12a6, Kif1a and Kif5a) [13, 21, 29, 31, 40–42, 52].