Treatment of rat model of acute pancreatitis, challenged with 75 μg/kg cholecystokinin, with 10 mg/kg Taraxacum officinale significantly reduced the expression of both IL-6 and TNF-α along with reduction of the ratio of the pancreatic weight to body weight and increase of both heat shock protein (HSP) 60 and HSP70 level in pancreatis [29]. This evidence concerns the gene CCK and acute pancreatitis.