PDHA1 and Familial prostate cancer: The 3-year overall survival (OS) rate of the 88 prostate cancer patients was 66.4%, with 48 deaths observed during the follow-up period.It was demonstrated that the patients with reduced PDHA1 protein expression in the tumor tissue had worse OS than the patients with strong positive PDHA1 protein expression inthe tumor (P < 0.05; Figure 6B).