When the serum levels of CRP, homocysteine and Klotho were compared among subjects, Klotho was the only marker to display different levels [72% higher among individuals affected by MI; p<0.001; d=1.6 (0.9 – 2.6)] according to a previous history of AMI (Figure 1). The gene discussed is CRP; the disease is myocardial infarction.