FLT3 and acute myeloid leukemia: Jiang et al. developed a targeted nanoparticle system, FLT3 ligand (FLT3L)-conjugated G7 poly nanosized dendriplex encapsulating miR-150, and demonstrated that the system selectively targets FLT3-overexpressing AML cells and efficiently inhibits cell viability and induces apoptosis both in vitro and in vivo [149].