NOTCH1 and B-cell chronic lymphocytic leukemia: In order to calculate the sensitivity of our assay to other exon 34 NOTCH1 insertions and deletions, given that the only mutation detected in CLL patients in our study was c.7544_7545delCT, we evaluated three samples from patients with T-acute lymphoblastic leukemia (T-ALL), known to harbor insertions and deletions in NOTCH1 exon 34.