However, Wu et al. [15], who carried out a studies on non smoker and non drinker women, reported that individuals with the c2/c2 genotype of CYP2E1*5 had a lower BC risk than that of c1/c1 (OR = 0.24, 95% CI = 0.08–0.74). The gene discussed is CYP2E1; the disease is breast cancer.