Aside from the above limitations, this meta-analysis suggests that CYP2E1*6 Dra I (D/C) polymorphism might be associated with increased BC risk, individuals with D/C and C/C + D/C genotypes or carried at least one C allele of CYP2E1*6 Dra I (D/C) polymorphism had a significant higher susceptibility to develop BC, in Caucasians, particularly. The gene discussed is CYP2E1; the disease is breast cancer.