Interestingly, when considering the CYP2E1*6 polymorphism, our study found that individuals with the D/C and C/C + D/C genotype had a significantly higher risk of BC compared to those with the D/D genotype, similar increased result was also found in the C allele carriers when compared with the D allele carriers, especially in Caucasian population. The gene discussed is CYP2E1; the disease is breast cancer.