Polysome profiles of Huh7 PKR ko cell clone 2#3, in which DENV replication levels were similar to those of parental cells (Fig. S6D), showed a similar reduction of polysomal RNAs throughout the course of infection (Fig. 4C), as observed for the parental Huh7 cells (Fig. 1B). Here, EIF2AK2 is linked to infection.