These results were also applicable in the RA population included in the study, as a total of 109 (21.3%) patients had a disease activity deviation from compatible to remission to low, low to moderate, or moderate to high, when DAS 28 was calculated using CRP = 9 mg/L, comparing with actual values of CRP, if the reporting limit has not been reduced to <3 mg/L. This evidence concerns the gene CRP and rheumatoid arthritis.