IL10 and hyperinsulinemic hypoglycemia, familial, 4: In support of these epidemiological findings, we established a mouse model that provided evidence for pregnancy complications in which genetic stress of IL-10 deficiency combined with exposure to Aroclor 1254 (A-1254), a mixture of more than 100 PCB congeners, resulted in preterm birth, fetal growth restriction, loss of righting reflex, and increase in amniotic fluid accumulation11.