GPT and Thrombocytopenia: Treatment-related grade 3 AEs occurred in 3 patients at the higher dose levels, including: eye pain, photophobia, and inflammation (n = 1; 4.34 mg/kg); increased alanine aminotransferase and increased blood alkaline phosphatase (n = 1; 5.42 mg/kg); and thrombocytopenia (n = 1, 6.5 mg/kg).