Evidence from these studies for inhibiting zinc mediated amyloid β-protein fibrillogenesis and cytotoxicity by serum albumin support the hypothesis that Cyclo-Z, which contains dipeptides similar to serum albumin may be helpful in preventing and treating AD, based on the fact that Cyclo-Z contains high amounts of histidine to chelate zinc and thus stimulate intestinal zinc absorption. The gene discussed is ALB; the disease is Alzheimer disease.