BECN1 and neoplasm: In our study, high Beclin-1 expression was significantly correlated with tumor size (p = 0.001), histological grade (p < 0.001), LN metastasis (p < 0.001), TNM stage (p < 0.001), VCE (p = 0.013), and high SIRT1 expression (p < 0.001).