To study in vivo the cardiac transcriptional programs in the absence of iASPP, we used the wa3 mice that carry spontaneous AR mutation in Ppp1r13l. These mice possess similar phenotype to the CCS patients with wavy hair and fatal post‐natal progressive DCM (Herron et al, 2005; Toonen et al, 2012; Appendix Fig S2). This evidence concerns the gene AR and familial dilated cardiomyopathy.