Constitutively activated Stat3 in ABC-DLBCL is associated with poor survival [15]; moreover, Stat3 activation is a biomarker for poor survival in DLBCL after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) treatment [16]. The gene discussed is STAT3; the disease is aneurysmal bone cyst.