There was only a trend towards increased plasma fibulin-1 levels when comparing in HF patients with DM vs non DM (P = 0.07), although impaired glucose metabolism assessed by presence of IGT and DM were associated with equivalent elevated mean fibulin-1 levels 61 ± 16 μg/mL vs. 60 ± 19 μg/mL, respectively compared to HF patients with NGT 52 ± 13 μg/mL (P = 0.01). Here, FBLN1 is linked to diabetes mellitus.