Data indicates that the CD8 T cell response to viral infection is diminished at day 4 post-infection with a notable decrease in CD8 T cell proliferation response (Fig 2I, p = 0.056) and lack of significant increase in CD8 cell number at day 4 and 10 post-infection after burn injury compared to naïve mice (Fig 2L). This evidence concerns the gene CD8A and infection.