TCF7L2 and type 2 diabetes mellitus: Initial analysis was performed with an adjustment for age and gender, which resulted in four loci showing statistically significant associations with T2D (Supplementary Table S1) at nominal significance levels (p < 0.05); TCF7L2 rs7901695 [odds ratio (OR) (95% confidence interval (CI)) 1.3 (1.08–1.55) p-value = 0.005], FTO rs8050136 [OR (95% CI) 1.34 (1.11–1.61) p-value = 0.002], HHEX rs5015480 [OR (95% CI) 1.36 (1.13–1.62) p-value = 0.001] and SLC30A8 rs13266634 [OR (95% CI) 1.31 (1.08–1.6) p-value = 0.007].