Although the mechanisms are not completely understood, replication stress in cancer cells may be the result of activation of oncogenes such as resistance to audiogenic seizures (RAS), v-myc avian myelocytomatosis viral oncogene homolog (MYC), cyclin-dependent kinases (CDKs) and CYCLINs [134,135,136,137,138,139,140,141,142,143,144]. This evidence concerns the gene MYC and cancer.