To further investigate the tumorigenic roles of KANK1, we knocked down KANK1 expression in an immortalized benign schwannoma cell line, HEI-19330, using shRNAs against KANK1. Consistently, there was an increase of cell growth rate in KANK1-knocked-down cells compared to the non-silencing control (Fig. 1g–i). This evidence concerns the gene KANK1 and schwannoma.