We then compared the TGI induced by these affinity-modulated monospecific EGFR/NMGC DuetMabs with the TGI mediated by their corresponding bispecific EGFR/HER2 DuetMab counterparts in single-flank tumor xenografts carrying only the double-positive NCI-H358 tumors. This evidence concerns the gene ERBB2 and neoplasm.