In addition, in another tissue array with known breast cancer subtypes, high protein expressions of DUB3 and SNAIL1 were both positively correlated with basal-like breast cancer type (Supplementary Fig. 5e,f), which is consistent with the role of DUB3 in promoting basal-like phenotype conversion we observed in Fig. 4a,b. This evidence concerns the gene SNAI1 and breast cancer.