The induced expression of angiotensinogen (AGT, 4.5-fold) in the kidney and the overall dramatic changes in the expression of surface molecules involved in cell adhesion and migration (CD9, CD81, CD63, CD166) together with the elevated level of myeloid cells in HD individuals may indicate accompanying cell migration into the SP as a main secondary lymphoid organ of salmonid fish. This evidence concerns the gene CD81 and Huntington disease.