CD8A and chronic obstructive pulmonary disease: A significant loss of GCR in CD8+CD28null NKT-like cells was noted in both COPD patients and controls compared with CD8+CD28+ NKT-like cells (mean ± SEM: 9 ± 4% CD8+GCR+CD28null NKT-like cells vs. 39 ± 7% CD8+GCR+CD28+ NKT-like cells in COPD).