However, currently there is a dearth of study material regarding the role of “CMA miRNAs” in PD pathogenesis apart from the only one study that showed the up-regulation of one of them resulted in the knock-down of hsc70 and increased levels of asyn in human SH-SY5Y neuroblastoma cells (Li et al., 2014). The gene discussed is HSPA8; the disease is Parkinson disease.