ASCL1 and neuroblastoma: As neuroblastomas are also genetically characterized based on their genomic MYCN amplification status and given the observed correlation with hASH1 (Supplementary Figure S2), the Kelly cells with the MYCN-amplified genome and the MYCN-non-amplified SH-SY5Y cells also enabled us to dissect the contribution of hASH1 independent of MYCN amplification.