Jumpy/MTMR14 PI3-phosphatase and Dynamin-2 (DNM2) GTPase, two causative genes of human centronuclear myopathy, are required for not only T-tubule maintenance but also proper progression of autophagy (Dowling et al., 2010; Durieux et al., 2012). This evidence concerns the gene MTMR14 and centronuclear myopathy.