Furthermore, previous studies in our laboratory have shown that the CD2− subset of bovine NK cells are preferentially activated following in vitro co‐culture with Bacillus Calmette–Guérin‐infected dendritic cells42 and Mycobacterium bovis‐infected dendritic cells.30 Therefore, CD2− NK cells may migrate from sites of vaccination or infection to draining lymph nodes where they could interact with populations of antigen‐presenting cells and egress via the efferent lymphatic vessel. This evidence concerns the gene CD2 and infection.