But, p27Kip1 expression was not correlated with the clinicopathological characteristics in NPC, although IHC analysis result showed that p27Kip1 expression was attenuated in NPC patients and statistical analysis data confirmed that the expression of p27kip1 was inversely related to Cks1 in NPC. The gene discussed is CDKN1B; the disease is nasopharyngeal carcinoma.