Expression of SIRT1 and STAT3 was significantly higher in the gastric cancer tissues than in the paired normal gastric mucosa for patients in both the GSE63089 (p < 0.001 for both SIRT1 and STAT3) and GSE29272 (p = 0.003 for SIRT1 and p < 0.001 STAT3) as shown in Supplementary Figures 3–6. This evidence concerns the gene SIRT1 and gastric cancer.