ALK and mature T-cell and NK-cell non-Hodgkin lymphoma: Liu et al proposed an 11-miRNA signature including 4 upregulated (miR-210, miR-197, miR-191, and miR-512-3p) and 7 downregulated miRNA (miR-451, miR- 146a, miR-22, miR-455-3p, miR-455-5p, miR-143, and miR-494), which distinguished ALK negative patients from PTCL-NOS with a 90% probability [56].