ALK positive ALCL cases displayed recurrent 17p and 17q24-qter gains and 4q13-q21, and 11q14 losses, gains of 1q and 6p21 were more frequently observed in ALK negative ALCL, whereas gains of chromosome 7 and 6q and 13q losses were seen in both types of ALCL tumors. The gene discussed is ALK; the disease is anaplastic large cell lymphoma.