Differential expression of proteins also discriminates between low and high Gleason scores, as, for instance, the set of KRT 7/8/18, HSPD1, HSPBP1, GST-π, PPA2, NDPK1, MTX2 - found upregulated in high Gleason scores PCa by 2D-PAGE and LC-MS [74], or Bax, Smac/Diablo phosphorylated Bcl2 and STAT3 - used for prognosis and therapy stratification [70] by a combination of microarray and LCMS. This evidence concerns the gene GSTP1 and posterior cortical atrophy.