TRPM7 and glioblastoma: In the current study, we report that naltriben: 1) potentiates endogenous TRPM7 channel activity and induces Ca2+ influx in the widely used U87 human glioblastoma (GBM) cell line; 2) enhances U87 migration and invasion; and 3) upregulates the MAPK/ERK signaling pathway.