TWIST1 and neoplasm: At day 35 post-radiation, the average size of tumors in the Eca109R/sh-Twist + IR mouse group was 140.19 ± 73.25 mm3, which was significantly smaller than the average tumor size of 477.89 ± 156.41 mm3 in the Eca109R/sh-NC + IR group (Figure 4D).