This is in accordance with Forsberg et al., who demonstrated a significant correlation of histological tumor vascularity and CEUS measurements with non-targeted ultrasound contrast media in a recent study with breast tumors, by correlating the ultrasonic fractional breast tumor vascularity (FV = number of color pixels relative to the total number of pixels within the breast mass) and CD31 [38]. The gene discussed is PECAM1; the disease is breast neoplasm.