This is in accordance with Baetke et al., who showed in their study with heterotopic squamous cell carcinoma xenografts in nude mice under anti-VEGF antibody therapy 8 minutes after BR55 MB injection a significant lower amount of specifically bound BR55 MB in treated tumors compared to the control group on day 4, day 7 and day 14 [21]. The gene discussed is VEGFA; the disease is squamous cell carcinoma.