Cai et al. found that down-regulation of miR-124 resulted in an increase in phosphorylated FAK, MMP2, vimentin, and N-cadherin levels in U87 cells through CAPN4, and that miR-124 suppressed the migration and invasion of glioma cells in vitro via CAPN4 [34]. The gene discussed is CAPNS1; the disease is central nervous system cancer.