HSPB8 and Familial prostate cancer: Expression analysis performed using real-time RT-PCR showed that HSPB8 mRNA is highly expressed in iPSCs, in BC cells (MCF-7) and in hepatocellular carcinoma (HepG2), while its expression is much lower in prostate cancer (PC) cells (PC3 and DU145 cells) and in melanoma cells (BML) (Figure 1, panel A).