The pro-migratory activity of HSPB8 in cancer cells migration has also been described in ovarian cancer (SKOV3.ip1) cells in which it was demonstrated that HSPB8 acts as a positive regulator in TGF-β -induced migration of ovarian cancer cells and directs ovarian cancer toward progression; as expected, HSPB8 silencing had the opposite effects in these cells [42]. The gene discussed is TGFB1; the disease is ovarian carcinoma.