Interestingly, expression of the HSPD1 gene encoding HSP60 was upregulated and SELENBP1 downregulated in human DKD, according to the Nephromine database, further suggesting potential common pathogenic pathways between DKD and colon cancer (http://www.nephromine.org/). The gene discussed is HSPD1; the disease is malignant colon neoplasm.