By taking a complementary approach and looking at genes previously shown to be differentially spliced in breast cancer we also observed a high level of concordance, for example Tenascin C, CD44, CD47, RELA, PTK2, ESR1, SYK, BRCA1, LARP1 and ADD39, 45, 46, 47, 48, 49, 50, 51, 52. This evidence concerns the gene BRCA1 and breast carcinoma.