LMX1B and Alzheimer disease: We sequenced exons 4 to 6 of LMX1B that encode for the DNA binding domain of LMX1B protein in 130 additional families with non-syndromic FSGS, we did not find additional families with mutations in LMX1B, thus mutations in exons 4 to 6 of LMX1B are responsible for 1–2% of AD FSGS in our cohort.