Reiner et al. later demonstrated that [18F]-BO could accurately measure the extent of PARP-1 expression in a variety of xenograft tumour models in mice and showed that uptake of [18F]-BO in ovarian (A2780) xenograft tumours was markedly reduced after administration of Olaparib (Fig. 6) [83]. This evidence concerns the gene PARP1 and neoplasm.